Write a 11 pages paper on questions concerning biology. Different species, just like strains within the different species, react variably to specific toxicants because of the differences that they have in their respective metabolism. Other factors like absorption and elimination also determine their reactions. Young animals have an underdeveloped system of the microsomal enzyme. This contributes to the compromise of the translocation and metabolism of xenobiotic agents. Species, health, and age cause differences in the capabilities to clear both the renal and the hepatic system along with the permeability of membranes. The amount needed by a xenobiotic agent for pathology to occur has a direct relationship with the weight of the body. With massive body weight, a relative increase in the toxicity of a compound occurs disproportionately. The rise in the level of toxicity takes place per unit of body mass. The surface area that the body has may have a relationship with the amount of the toxin. It is imperative to note that there does not exist any measurement parameter that applies to every situation (Singh, 2012, 233).


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