Complete 6 pages APA formatted article: Ugi Reaction. The history of the Ugi reaction dates back to the middle of the 20th century, but it was not before the beginning of the 21st century that its value and benefits for the evolution of organic chemistry were consistently recognized. Ivar Ugi is believed to be the father of all multicomponent reactions [28]. Ugi is also considered the grandfather of the whole combinatorial chemistry [29]. Today’s chemists rely on the advantages of the Ugi reaction, to synthesize diverse collections/ libraries of biologically interesting products. This is particularly the case of the drug industry, which relies on the premise of discovery and innovations and demands fast methods of chemical analysis and synthesis of complex molecules.


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